{"id":2272,"date":"2025-11-04T07:07:55","date_gmt":"2025-11-04T07:07:55","guid":{"rendered":"https:\/\/drsevalkarasati.com\/?page_id=2272"},"modified":"2026-03-12T09:13:17","modified_gmt":"2026-03-12T09:13:17","slug":"autologous-fibroblast-and-stem-cell-treatment","status":"publish","type":"page","link":"https:\/\/drsevalkarasati.com\/en\/anti-aging-and-cosmetic-procedures\/autologous-fibroblast-and-stem-cell-treatment\/","title":{"rendered":"Autologous Fibroblast and Stem Cell Treatment"},"content":{"rendered":"\n\t<section class=\"section\" id=\"section_52370616\">\n\t\t<div class=\"section-bg fill\" >\n\t\t\t\t\t\t\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\n  <div id=\"page-header-1561807163\" class=\"page-header-wrapper\">\n  <div class=\"page-title dark simple-title\">\n\n    \n    <div class=\"page-title-inner container align-center text-center flex-row-col medium-flex-wrap\" >\n              <div class=\"title-wrapper is-larger flex-col\">\n          <h1 class=\"entry-title mb-0\">\n            Autologous Fibroblast and Stem Cell Treatment in Ankara, Turkey          <\/h1>\n        <\/div>\n                    <div class=\"title-content flex-col\">\n        <div class=\"title-breadcrumbs pb-half pt-half\"><\/div>      <\/div>\n    <\/div>\n\n       <\/div>\n    <\/div>\n  \n\t\t<\/div>\n\n\t\t\n<style>\n#section_52370616 {\n  padding-top: 0px;\n  padding-bottom: 0px;\n  background-color: #8a817c;\n}\n<\/style>\n\t<\/section>\n\t\n\n\t<section class=\"section\" id=\"section_564471747\">\n\t\t<div class=\"section-bg fill\" >\n\t\t\t\t\t\t\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\n<div class=\"row\"  id=\"row-1934284878\">\n\n\t<div id=\"col-173479746\" class=\"col large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<p>Autologous fibroblast and stem cell treatment is an advanced biotechnological application in which biological materials obtained from a person\u2019s own cells are used for skin rejuvenation and tissue renewal. By targeting regeneration at the cellular level, this treatment creates a natural anti-aging effect.<\/p>\n<p>In autologous fibroblast treatment, fibroblast cells are multiplied in a laboratory environment from a small skin sample taken from the patient. These cells are injected into the skin to increase collagen and elastin production. The application is an effective method for reducing fine wrinkles and skin laxity.<\/p>\n<p>Stem cell treatment is performed using mesenchymal stem cells obtained from adipose tissue. These cells accelerate tissue repair and reduce the signs of aging on the skin. At the same time, they also have a supportive effect in the treatment of wounds, burns, and scars.<\/p>\n<p>Since both treatments are autologous, the risk of allergic reaction is low. The application should be performed under sterile conditions and by experienced specialists. Treatment results usually appear within a few months and provide long-term improvement in skin quality.<\/p>\n<table>\n<tbody>\n<tr>\n<td>What You Need to Know<\/td>\n<td>Information<\/td>\n<\/tr>\n<tr>\n<td>What is autologous fibroblast and stem cell treatment<\/td>\n<td>It is a regenerative treatment method applied for skin renewal and rejuvenation by multiplying fibroblast or stem cells obtained from samples taken from the person\u2019s own tissue (generally from the skin behind the ear or adipose tissue) in a laboratory environment and reinjecting them into the same person.<\/td>\n<\/tr>\n<tr>\n<td>Role of fibroblast cells<\/td>\n<td>Fibroblasts are the main cells that provide collagen, elastin, and connective tissue production in the skin. Their number and activity decrease with age. By increasing the number of these cells through autologous fibroblast injections, the skin\u2019s natural renewal capacity is supported.<\/td>\n<\/tr>\n<tr>\n<td>Effect of stem cells<\/td>\n<td>Stem cells are special cells with the ability to transform into different cell types. They accelerate repair and renewal in the skin, supporting cell regeneration and tissue integrity. Mesenchymal stem cells obtained especially from adipose tissue are used for aesthetic purposes.<\/td>\n<\/tr>\n<tr>\n<td>When it is preferred<\/td>\n<td>It is used in cases such as age-related loss of skin elasticity, deep wrinkles, skin sagging, scars and scar tissue (acne scars, surgical scars), tissue collapse, sun damage, fine lines, and decreased skin quality.<\/td>\n<\/tr>\n<tr>\n<td>Application process<\/td>\n<td>First, a small tissue sample is taken (usually under local anesthesia). Fibroblasts or stem cells are multiplied in a laboratory environment (this takes approximately 3\u20134 weeks). The obtained cells are applied to the determined areas by injection. It is generally performed in 2\u20133 sessions.<\/td>\n<\/tr>\n<tr>\n<td>Advantages<\/td>\n<td>&#8211; Since the person\u2019s own cells are used, there is no risk of allergy or rejection. &#8211; It does not contain fillers or synthetic substances. &#8211; It deeply repairs the skin structure and provides natural renewal. &#8211; Its effect is long-lasting (it may last 2\u20133 years).<\/td>\n<\/tr>\n<tr>\n<td>Post-application process<\/td>\n<td>Mild redness, swelling, and bruising may occur after the procedure. It usually improves within 1\u20133 days. Skin renewal begins within weeks and continues to increase over time. The results appear naturally and gradually.<\/td>\n<\/tr>\n<tr>\n<td>Who it is suitable for<\/td>\n<td>It is suitable for adult individuals who have signs of aging on their skin, experience deep wrinkles or tissue loss, do not want artificial fillers, and are in good general health.<\/td>\n<\/tr>\n<tr>\n<td>Things to consider<\/td>\n<td>The procedure should be performed by experienced specialists under sterile laboratory conditions. Results may vary from person to person. Detailed skin and health evaluation should be performed before the application.<\/td>\n<\/tr>\n<tr>\n<td>Realistic expectations<\/td>\n<td>Skin rejuvenation and improvement develop naturally over time. Instead of miraculous or sudden effects, long-term structural improvement should be targeted. If necessary, it can be supported with maintenance sessions.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-173479746 > .col-inner {\n  margin: 0px 0px -45px 0px;\n}\n<\/style>\n\t<\/div>\n\n\t\n<\/div>\n\t\t<\/div>\n\n\t\t\n<style>\n#section_564471747 {\n  padding-top: 30px;\n  padding-bottom: 30px;\n}\n<\/style>\n\t<\/section>\n\t\n\n\t<section class=\"section\" id=\"section_597983514\">\n\t\t<div class=\"section-bg fill\" >\n\t\t\t\t\t\t\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\r\n\r\n<div class=\"row\"  id=\"row-1110300944\">\r\n\r\n\n\t<div id=\"col-219832754\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\" style=\"background-color:#8a817c;\" >\n\t\t\t\n\t\t\t\r\n\r\n<div class=\"row align-middle\"  id=\"row-1701240097\">\r\n\r\n\n\t<div id=\"col-1844205173\" class=\"col medium-5 small-12 large-5\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\r\n\r\n\t<div class=\"img has-hover x md-x lg-x y md-y lg-y\" id=\"image_279040172\">\n\t\t\t\t\t\t\t\t<div class=\"img-inner dark\" >\n\t\t\t<img decoding=\"async\" width=\"782\" height=\"800\" src=\"https:\/\/drsevalkarasati.com\/wp-content\/uploads\/2025\/11\/bt0qauqqvf2c9eyqvf2e-e1763480905624-782x800.webp\" class=\"attachment-large size-large\" alt=\"ankara dermatoloji doktoru seval karasat\u0131\" srcset=\"https:\/\/drsevalkarasati.com\/wp-content\/uploads\/2025\/11\/bt0qauqqvf2c9eyqvf2e-e1763480905624-782x800.webp 782w, https:\/\/drsevalkarasati.com\/wp-content\/uploads\/2025\/11\/bt0qauqqvf2c9eyqvf2e-e1763480905624-391x400.webp 391w, https:\/\/drsevalkarasati.com\/wp-content\/uploads\/2025\/11\/bt0qauqqvf2c9eyqvf2e-e1763480905624-768x785.webp 768w, https:\/\/drsevalkarasati.com\/wp-content\/uploads\/2025\/11\/bt0qauqqvf2c9eyqvf2e-e1763480905624.webp 882w\" sizes=\"(max-width: 782px) 100vw, 782px\" \/>\t\t\t\t\t\t\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\n<style>\n#image_279040172 {\n  width: 100%;\n}\n<\/style>\n\t<\/div>\n\t\r\n\r\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-1844205173 > .col-inner {\n  margin: 0px 0px 0px 0px;\n}\n@media (min-width:550px) {\n  #col-1844205173 > .col-inner {\n    margin: 0px 0px -30px 0px;\n  }\n}\n<\/style>\n\t<\/div>\n\n\t\r\n\n\t<div id=\"col-1221159999\" class=\"col medium-7 small-12 large-7\"  >\n\t\t\t\t<div class=\"col-inner dark\"  >\n\t\t\t\n\t\t\t\r\n\r\n\t<div id=\"text-2080664501\" class=\"text\">\n\t\t\r\n<div><strong>Specialist Dr. Seval Karasat\u0131<\/strong><\/div>\r\n\t\t\n<style>\n#text-2080664501 {\n  font-size: 1.85rem;\n  text-align: center;\n}\n@media (min-width:550px) {\n  #text-2080664501 {\n    font-size: 2.5rem;\n    text-align: left;\n  }\n}\n<\/style>\n\t<\/div>\n\t\r\n\t<div id=\"text-1576285571\" class=\"text\">\n\t\t\r\n\r\n<span style=\"font-weight: 400;\">Dr. Seval Karasat\u0131 is a dermatology (skin diseases) specialist in Ankara specializing in skin health, hair and nail diseases, aesthetic dermatology, and laser applications. With her scientifically based approach and aesthetic perspective, she offers personalized treatment plans for each of her patients.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">In the field of dermatology, Dr. Seval Karasat\u0131 specializes not only in common skin problems such as acne, rosacea, eczema, allergic skin diseases, and hair loss, but also in mole monitoring and the early diagnosis of skin cancers. She provides effective solutions to her patients with modern devices and up-to-date treatment methods.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Serving as a dermatology specialist in Ankara, Dr. Seval Karasat\u0131 is also experienced in aesthetic dermatology procedures. She applies holistic treatments aimed at skin renewal and rejuvenation with procedures such as fillers, PRP, mesotherapy, gold needle, and laser treatments.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Dr. Seval Karasat\u0131 conducts a comprehensive evaluation for each patient and shapes the treatment process according to personal needs. Her goal is not only to treat diseases but also to help achieve a healthy, vibrant, and aesthetically balanced skin appearance.<\/span>\r\n\r\n\t\t\n<style>\n#text-1576285571 {\n  text-align: center;\n}\n@media (min-width:550px) {\n  #text-1576285571 {\n    text-align: left;\n  }\n}\n<\/style>\n\t<\/div>\n\t\r\n<a href=\"https:\/\/api.whatsapp.com\/send\/?phone=905323677805\" class=\"button primary expand show-for-small\" target=\"_blank\" rel=\"noopener\">\n\t\t<span>Create an Appointment<\/span>\n\t<\/a>\n\r\n\r\n<a href=\"https:\/\/api.whatsapp.com\/send\/?phone=905323677805\" class=\"button primary hide-for-small\" target=\"_blank\" rel=\"noopener\">\n\t\t<span>Create an Appointment<\/span>\n\t<\/a>\n\r\n\r\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-1221159999 > .col-inner {\n  margin: 0px 0px -30px 0px;\n}\n@media (min-width:550px) {\n  #col-1221159999 > .col-inner {\n    margin: 0px 0px -30px 0px;\n  }\n}\n<\/style>\n\t<\/div>\n\n\t\r\n\r\n<\/div>\r\n\r\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-219832754 > .col-inner {\n  padding: 20px 30px 10px 30px;\n  margin: 0px 0px -30px 0px;\n  border-radius: 30px;\n}\n<\/style>\n\t<\/div>\n\n\t\r\n\r\n<\/div>\r\n\r\n\t\t<\/div>\n\n\t\t\n<style>\n#section_597983514 {\n  padding-top: 0px;\n  padding-bottom: 0px;\n}\n<\/style>\n\t<\/section>\n\t\n\n\t<section class=\"section\" id=\"section_1841425072\">\n\t\t<div class=\"section-bg fill\" >\n\t\t\t\t\t\t\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\n<div class=\"row\"  id=\"row-47937512\">\n\n\t<div id=\"col-1667629650\" class=\"col large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_89 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #ffffff;color:#ffffff\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #ffffff;color:#ffffff\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/drsevalkarasati.com\/en\/anti-aging-and-cosmetic-procedures\/autologous-fibroblast-and-stem-cell-treatment\/#What_Is_Autologous_Fibroblast_and_Stem_Cell_Treatment\" >What Is Autologous Fibroblast and Stem Cell Treatment?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/drsevalkarasati.com\/en\/anti-aging-and-cosmetic-procedures\/autologous-fibroblast-and-stem-cell-treatment\/#Why_is_autologous_cellular_treatment_safe\" >Why is autologous cellular treatment safe?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/drsevalkarasati.com\/en\/anti-aging-and-cosmetic-procedures\/autologous-fibroblast-and-stem-cell-treatment\/#What_is_the_difference_between_the_main_autologous_cells_used_in_skin_rejuvenation_namely_Fibroblasts_and_Stem_Cells\" >What is the difference between the main autologous cells used in skin rejuvenation, namely Fibroblasts and Stem Cells?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/drsevalkarasati.com\/en\/anti-aging-and-cosmetic-procedures\/autologous-fibroblast-and-stem-cell-treatment\/#How_does_Autologous_Fibroblast_Treatment_AFT_work\" >How does Autologous Fibroblast Treatment (AFT) work?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/drsevalkarasati.com\/en\/anti-aging-and-cosmetic-procedures\/autologous-fibroblast-and-stem-cell-treatment\/#How_are_fibroblast_cells_obtained_and_produced_for_treatment\" >How are fibroblast cells obtained and produced for treatment?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/drsevalkarasati.com\/en\/anti-aging-and-cosmetic-procedures\/autologous-fibroblast-and-stem-cell-treatment\/#In_which_areas_is_autologous_fibroblast_treatment_most_effective\" >In which areas is autologous fibroblast treatment most effective?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/drsevalkarasati.com\/en\/anti-aging-and-cosmetic-procedures\/autologous-fibroblast-and-stem-cell-treatment\/#Is_autologous_fibroblast_treatment_safe_and_how_long-lasting_are_its_results\" >Is autologous fibroblast treatment safe and how long-lasting are its results?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/drsevalkarasati.com\/en\/anti-aging-and-cosmetic-procedures\/autologous-fibroblast-and-stem-cell-treatment\/#What_is_Adipose-Derived_Stem_Cell_Treatment_ADCT_and_how_does_it_work\" >What is Adipose-Derived Stem Cell Treatment (ADCT) and how does it work?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/drsevalkarasati.com\/en\/anti-aging-and-cosmetic-procedures\/autologous-fibroblast-and-stem-cell-treatment\/#How_are_Stem_Cells_obtained_for_treatment\" >How are Stem Cells obtained for treatment?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/drsevalkarasati.com\/en\/anti-aging-and-cosmetic-procedures\/autologous-fibroblast-and-stem-cell-treatment\/#Are_there_risks_or_limitations_of_Stem_Cell_treatment\" >Are there risks or limitations of Stem Cell treatment?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/drsevalkarasati.com\/en\/anti-aging-and-cosmetic-procedures\/autologous-fibroblast-and-stem-cell-treatment\/#Which_autologous_treatment_is_better_Fibroblast_or_Stem_Cell\" >Which autologous treatment is better: Fibroblast or Stem Cell?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/drsevalkarasati.com\/en\/anti-aging-and-cosmetic-procedures\/autologous-fibroblast-and-stem-cell-treatment\/#Can_autologous_treatments_be_combined_with_procedures_such_as_Laser_or_Microneedling\" >Can autologous treatments be combined with procedures such as Laser or Microneedling?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/drsevalkarasati.com\/en\/anti-aging-and-cosmetic-procedures\/autologous-fibroblast-and-stem-cell-treatment\/#Frequently_Asked_Questions\" >Frequently Asked Questions<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"What_Is_Autologous_Fibroblast_and_Stem_Cell_Treatment\"><\/span>What Is Autologous Fibroblast and Stem Cell Treatment?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Autologous fibroblast and stem cell treatment is a regenerative method applied by multiplying cells obtained from the person\u2019s own tissue in a laboratory environment and injecting them under the skin. This treatment is especially preferred to reduce signs of aging, increase skin elasticity, and support tissue repair. Since it is a natural and biological approach, it can provide long-lasting and safe results.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Why_is_autologous_cellular_treatment_safe\"><\/span>Why is autologous cellular treatment safe?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Autologous cellular treatment is one of the cornerstones of modern regenerative medicine. Its principle is very simple: using cells or tissues taken from an individual\u2019s own body. These cells are sometimes used as they are and sometimes passed through a laboratory process (for example, multiplied or enriched) and then given back to the same individual for a treatment or cosmetic purpose.<\/p>\n<p>The greatest strength of this approach is biological compatibility. It is not possible for your body to perceive its own cell as &#8220;foreign.&#8221; Some synthetic fillers or animal-derived (for example bovine) collagens used in the past carried the risk of causing a reaction in the body. For this reason, allergy testing had to be performed before such treatments. Risks such as allergic reactions, abscess formation, or the body trying to reject that substance (foreign body granuloma) were always on the table.<\/p>\n<p>Autologous treatments completely overcome these limitations. Since the body recognizes its own cells, the risk of allergy or hypersensitivity disappears. At the same time, there is no risk of external contamination or infection (as long as the procedure is performed under sterile conditions). This places autologous treatments in an extremely superior position in terms of safety profile. The main goal is to use the specific regenerative capacity of the selected cell type (fibroblast or stem cell) to repair damaged skin tissue, restore lost volume, and rejuvenate the skin as a whole.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_is_the_difference_between_the_main_autologous_cells_used_in_skin_rejuvenation_namely_Fibroblasts_and_Stem_Cells\"><\/span>What is the difference between the main autologous cells used in skin rejuvenation, namely Fibroblasts and Stem Cells?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>When we talk about cellular treatments in dermatology, we actually focus on two main cell groups: Dermal Fibroblasts and Adipose-Derived Stem Cells (ADSCs).<\/p>\n<p>These two cell groups use fundamentally completely different methods to renew the skin. Which treatment is chosen depends on the patient\u2019s needs and the targeted outcome.<\/p>\n<p>Think of it this way: Fibroblasts are like the &#8220;production factories&#8221; of the skin. Stem cells are more like &#8220;signal-giving managers&#8221; or &#8220;repair team chiefs&#8221;:<\/p>\n<p>Dermal Fibroblasts (Structural Factories)<\/p>\n<p>Fibroblasts are the main cells located in the dermis, the middle layer of our skin. They have only one basic task: to produce the support structure of the skin, the structure called the &#8220;Extracellular Matrix&#8221; (ECM). This structure consists of:<\/p>\n<ul>\n<li>Collagen (for the skin\u2019s strength and structure)<\/li>\n<li>Elastin (for the skin\u2019s elasticity)<\/li>\n<\/ul>\n<p>Glycosaminoglycans (for the skin\u2019s moisture-retention capacity)<\/p>\n<p>Fibroblast treatment (AFT) means adding more &#8220;production factories&#8221; directly into the skin. These cells are specialized cells designed to restore and repair the physically missing structure.<\/p>\n<p>Adipose-Derived Stem Cells (ADSCs) (Signal-Giving Managers)<\/p>\n<p>Stem cells, on the other hand (generally obtained from adipose tissue), unlike fibroblasts, do not directly produce a structural component (such as collagen). Their power comes from the signals they send to their environment. Stem cells secrete powerful signaling molecules into their surroundings. These signals do the following:<\/p>\n<ul>\n<li>Powerful anti-inflammatory effect<\/li>\n<li>Secretion of various growth factors<\/li>\n<li>Antioxidant effect<\/li>\n<li>Promotion of the formation of new blood vessels (Neoangiogenesis)<\/li>\n<\/ul>\n<p>Stem cell treatment (ADCT) means adding &#8220;manager&#8221; cells to the skin. These cells instruct the existing surrounding cells (including the existing fibroblasts) to &#8220;work harder,&#8221; &#8220;heal faster,&#8221; and &#8220;revitalize the area.&#8221; They promote the overall health and regeneration of the tissue.<\/p>\n<p>The clinical result of this mechanical difference is very important. Fibroblast treatment (AFT) offers an ideal direct replacement strategy for regional and deep structural deficiencies such as deep acne scars or established deep wrinkles. Stem cell treatment (ADCT), on the other hand, is superior for improving the overall quality of the skin (texture, elasticity, radiance) and globally enhancing skin health.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_does_Autologous_Fibroblast_Treatment_AFT_work\"><\/span>How does Autologous Fibroblast Treatment (AFT) work?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Autologous Fibroblast Treatment (AFT) is based on injecting the person\u2019s own healthy and youthful fibroblasts, multiplied in the laboratory, directly into the area where they are needed (for example into a wrinkle line or acne scar).<\/p>\n<p>These injected fresh &#8220;production factory&#8221; cells have two main roles:<\/p>\n<ul>\n<li>Direct Production: As soon as they are injected, they immediately begin to produce new collagen and elastin in the deficient area.<\/li>\n<li>Stimulation: They also stimulate the other existing fibroblast population in the area, which may have become &#8220;slowed down&#8221; or &#8220;tired&#8221; due to age, encouraging them to increase their production of supportive tissue.<\/li>\n<\/ul>\n<p>This is a dual-effect process that strengthens the architecture of the skin by both adding new workers and motivating the old ones. This treatment mimics the skin\u2019s own self-repair mechanism, but it does so in a much stronger and more concentrated way.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_are_fibroblast_cells_obtained_and_produced_for_treatment\"><\/span>How are fibroblast cells obtained and produced for treatment?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>One of the most important advantages of AFT is that the production process is logistically simple and reliable.<\/p>\n<ul>\n<li>Sample Collection (Sourcing)<\/li>\n<\/ul>\n<p>A major surgical procedure is not required to obtain fibroblasts. Generally, it is sufficient to take a single dermal punch biopsy (approximately 3-4 mm in diameter, a tiny piece of tissue) from a closed area that does not see the sun, such as behind the ear or the inner arm, under a small local anesthesia. This minimally invasive procedure provides a sufficient source of autologous cells for all future clinical applications (sometimes for 2-3 treatment sessions).<\/p>\n<ul>\n<li>Culture and Multiplication (Ex-Vivo)<\/li>\n<\/ul>\n<p>This tiny piece of tissue is sent to special cell laboratories approved by the Ministry of Health and having GMP (Good Manufacturing Practices) standards. Here, fibroblasts are separated from the tissue and begin to be multiplied in special nutrient media (culture environments).<\/p>\n<p>Fibroblasts are remarkably robust cells compared to stem cells. They multiply rapidly in the laboratory environment; the doubling time of a fibroblast population is on average between 16 and 24 hours. This is significantly faster than the proliferation rate of stem cells (48+ hours).<\/p>\n<p>These features (easy sourcing, robustness, rapid multiplication) make AFT a more accessible and reliable option. This production consistency also makes the &#8220;cell banking&#8221; model possible. That is, cells taken today can be multiplied and frozen and reused years later when needed (for example, for a booster dose 5 years later).<\/p>\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-1667629650 > .col-inner {\n  margin: 0px 0px -45px 0px;\n}\n<\/style>\n\t<\/div>\n\n\t\n<\/div>\n\t\t<\/div>\n\n\t\t\n<style>\n#section_1841425072 {\n  padding-top: 30px;\n  padding-bottom: 30px;\n}\n<\/style>\n\t<\/section>\n\t\n\n\t<section class=\"section\" id=\"section_1686159326\">\n\t\t<div class=\"section-bg fill\" >\n\t\t\t\t\t\t\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\r\n\r\n<div class=\"row\"  id=\"row-910755674\">\r\n\r\n\n\t<div id=\"col-1610017183\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner box-shadow-3\"  >\n\t\t\t\n\t<div class=\"is-border\"\n\t\tstyle=\"border-color:rgb(196, 135, 135);border-width:3px 3px 3px 3px;\">\n\t<\/div>\n\t\t\t\r\n\r\n<div class=\"row\"  id=\"row-1888898268\">\r\n\r\n\n\t<div id=\"col-586421475\" class=\"col medium-8 small-12 large-8\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\r\n\r\n\t<div id=\"text-2785379352\" class=\"text\">\n\t\t\r\n<div><strong>Contact Us for Anything You Wonder About Skin Health!<\/strong><\/div>\r\n\t\t\n<style>\n#text-2785379352 {\n  font-size: 2.25rem;\n  text-align: center;\n  color: #c48787;\n}\n#text-2785379352 > * {\n  color: #c48787;\n}\n@media (min-width:550px) {\n  #text-2785379352 {\n    text-align: left;\n  }\n}\n<\/style>\n\t<\/div>\n\t\r\n\r\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-586421475 > .col-inner {\n  padding: 10px 30px 0px 30px;\n  margin: 0px 0px -30px 0px;\n}\n@media (min-width:550px) {\n  #col-586421475 > .col-inner {\n    padding: 0px 0px 0px 30px;\n  }\n}\n<\/style>\n\t<\/div>\n\n\t\r\n\n\t<div id=\"col-1149201147\" class=\"col medium-4 small-12 large-4\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\r\n\r\n<a class=\"button success expand\" >\n\t\t<span>Contact via WhatsApp<\/span>\n\t<i class=\"icon-whatsapp\" aria-hidden=\"true\"><\/i><\/a>\n\r\n\r\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-1149201147 > .col-inner {\n  padding: 30px 30px 10px 30px;\n  margin: 0px 0px -30px 0px;\n}\n@media (min-width:550px) {\n  #col-1149201147 > .col-inner {\n    padding: 30px 30px 0px 0px;\n  }\n}\n<\/style>\n\t<\/div>\n\n\t\r\n\r\n<\/div>\r\n\r\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-1610017183 > .col-inner {\n  padding: 20px 0px 20px 0px;\n  margin: 0px 0px -30px 0px;\n}\n@media (min-width:550px) {\n  #col-1610017183 > .col-inner {\n    padding: 20px 20px 20px 20px;\n  }\n}\n<\/style>\n\t<\/div>\n\n\t\r\n\r\n<\/div>\r\n\r\n\t\t<\/div>\n\n\t\t\n<style>\n#section_1686159326 {\n  padding-top: 0px;\n  padding-bottom: 0px;\n}\n<\/style>\n\t<\/section>\n\t\n\n\t<section class=\"section\" id=\"section_1159772216\">\n\t\t<div class=\"section-bg fill\" >\n\t\t\t\t\t\t\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\n<div class=\"row\"  id=\"row-11564662\">\n\n\t<div id=\"col-740796305\" class=\"col large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h2><span class=\"ez-toc-section\" id=\"In_which_areas_is_autologous_fibroblast_treatment_most_effective\"><\/span>In which areas is autologous fibroblast treatment most effective?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Since fibroblast treatment focuses on directly correcting the lack of &#8220;structure,&#8221; it is particularly powerful in certain indications. Some of the conditions in which fibroblast treatment is most preferred and provides the best results are:<\/p>\n<ul>\n<li>Deep acne scars (depressed, atrophic scars)<\/li>\n<li>Nasolabial folds (lines around the nose)<\/li>\n<li>Marionette lines (lines running from the corners of the mouth to the chin)<\/li>\n<li>Prominent facial wrinkles (especially static, established rhytids)<\/li>\n<li>Depressed scars formed after surgery or trauma<\/li>\n<li>Areas experiencing regional volume loss in the skin<\/li>\n<li>Upper lip &#8220;barcode&#8221; lines<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"Is_autologous_fibroblast_treatment_safe_and_how_long-lasting_are_its_results\"><\/span>Is autologous fibroblast treatment safe and how long-lasting are its results?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Autologous treatments already have a very strong safety profile because of their biological origin. In clinical studies conducted for AFT, no serious side effects were reported other than temporary minimal redness or bruising at the injection site.<\/p>\n<p>An important advantage of AFT is that it has also been recognized by regulatory authorities. For example, the autologous fibroblast treatment called Azficel-T (commercially known as LaViv\u00ae) received approval from the U.S. Food and Drug Administration (FDA) for the correction of nasolabial folds (lines around the nose). This FDA approval is an important legal precedent showing that AFT is a proven, validated, personalized cell therapy product whose efficacy and safety have been demonstrated.<\/p>\n<p>Permanence:<\/p>\n<p>One of the most attractive aspects of this treatment is its durability. Clinical studies have documented that the improvements provided by AFT injections last at least 12 months.<\/p>\n<p>In a comprehensive study, significant improvement was observed after 6 months in patients treated for wrinkles and acne scars, and this effect remained stable for up to 24 months (2 years).<\/p>\n<p>Patient satisfaction data also support this durability. In a 5-year telephone follow-up, 65.2% of the participants treated for wrinkles still rated their treatment areas as &#8220;good&#8221; or &#8220;excellent.&#8221;<\/p>\n<p>However, the situation is slightly different in acne scar treatment. Satisfaction with acne scars dropped to 30% over the 5-year period. This does not mean that the treatment failed. It shows that complex and deep fibrotic tissues such as acne scars require a more complex repair process than wrinkle treatment and that periodic maintenance sessions may be needed in these patients.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_is_Adipose-Derived_Stem_Cell_Treatment_ADCT_and_how_does_it_work\"><\/span>What is Adipose-Derived Stem Cell Treatment (ADCT) and how does it work?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Adipose-derived cellular treatments (ADCT) drive dermatological rejuvenation primarily through their paracrine effects, that is, their ability to &#8220;send signals&#8221; from cell to cell. The injected stem cells (ADSCs) secrete powerful growth factors and anti-inflammatory molecules that improve the local tissue microenvironment.<\/p>\n<p>This biological signaling stimulates tissue renewal, encourages existing cells to secrete proteins such as collagen, increases the skin\u2019s moisture and density, and improves blood supply by supporting the formation of new capillaries (neoangiogenesis).<\/p>\n<p>The aim of this treatment is not to directly &#8220;fill&#8221; like fibroblasts, but to improve the overall quality and health of the skin. It is regarded as a promising minimally invasive method especially for increasing elasticity, firmness, and dermal thickness.<\/p>\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-740796305 > .col-inner {\n  margin: 0px 0px -45px 0px;\n}\n<\/style>\n\t<\/div>\n\n\t\n<\/div>\n\t\t<\/div>\n\n\t\t\n<style>\n#section_1159772216 {\n  padding-top: 30px;\n  padding-bottom: 30px;\n}\n<\/style>\n\t<\/section>\n\t\n\n\t<section class=\"section\" id=\"section_860371231\">\n\t\t<div class=\"section-bg fill\" >\n\t\t\t\t\t\t\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\r\n\r\n<div class=\"row\"  id=\"row-669146612\">\r\n\r\n\n\t<div id=\"col-2053454172\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner box-shadow-3\"  >\n\t\t\t\n\t<div class=\"is-border\"\n\t\tstyle=\"border-color:rgb(138, 129, 124);border-width:3px 3px 3px 3px;\">\n\t<\/div>\n\t\t\t\r\n\r\n<div class=\"row\"  id=\"row-227823046\">\r\n\r\n\n\t<div id=\"col-898500019\" class=\"col medium-8 small-12 large-8\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\r\n\r\n\t<div id=\"text-1215807990\" class=\"text\">\n\t\t\r\n<div><strong>Contact Us for Anything You Wonder About Skin Health!<\/strong><\/div>\r\n\t\t\n<style>\n#text-1215807990 {\n  font-size: 2.25rem;\n  text-align: center;\n  color: #8a817c;\n}\n#text-1215807990 > * {\n  color: #8a817c;\n}\n@media (min-width:550px) {\n  #text-1215807990 {\n    text-align: left;\n  }\n}\n<\/style>\n\t<\/div>\n\t\r\n\r\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-898500019 > .col-inner {\n  padding: 10px 30px 0px 30px;\n  margin: 0px 0px -30px 0px;\n}\n@media (min-width:550px) {\n  #col-898500019 > .col-inner {\n    padding: 0px 0px 0px 30px;\n  }\n}\n<\/style>\n\t<\/div>\n\n\t\r\n\n\t<div id=\"col-106256099\" class=\"col medium-4 small-12 large-4\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\r\n\r\n<a class=\"button success expand\" >\n\t\t<span>Contact via WhatsApp<\/span>\n\t<i class=\"icon-whatsapp\" aria-hidden=\"true\"><\/i><\/a>\n\r\n\r\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-106256099 > .col-inner {\n  padding: 30px 30px 10px 30px;\n  margin: 0px 0px -30px 0px;\n}\n@media (min-width:550px) {\n  #col-106256099 > .col-inner {\n    padding: 30px 30px 0px 0px;\n  }\n}\n<\/style>\n\t<\/div>\n\n\t\r\n\r\n<\/div>\r\n\r\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-2053454172 > .col-inner {\n  padding: 20px 0px 20px 0px;\n  margin: 0px 0px -30px 0px;\n}\n@media (min-width:550px) {\n  #col-2053454172 > .col-inner {\n    padding: 20px 20px 20px 20px;\n  }\n}\n<\/style>\n\t<\/div>\n\n\t\r\n\r\n<\/div>\r\n\r\n\t\t<\/div>\n\n\t\t\n<style>\n#section_860371231 {\n  padding-top: 0px;\n  padding-bottom: 0px;\n}\n<\/style>\n\t<\/section>\n\t\n\n\t<section class=\"section\" id=\"section_1606412315\">\n\t\t<div class=\"section-bg fill\" >\n\t\t\t\t\t\t\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\n<div class=\"row\"  id=\"row-579433176\">\n\n\t<div id=\"col-1818226012\" class=\"col large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<h2><span class=\"ez-toc-section\" id=\"How_are_Stem_Cells_obtained_for_treatment\"><\/span>How are Stem Cells obtained for treatment?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Unlike the simple punch biopsy in fibroblast treatment, the application of ADCT requires an initial surgical procedure: the collection of adipose tissue through liposuction. This is generally a more invasive procedure than fibroblast collection, usually from the abdomen or hips.<\/p>\n<p>The obtained fat (lipoaspirate) is then processed. As a result of this process, two types of products can be obtained:<\/p>\n<ul>\n<li>SVF (Stromal Vascular Fraction): A heterogeneous mixture obtained from adipose tissue containing many different cell types such as stem cells, immune cells, and preadipocytes. It can be used immediately.<\/li>\n<li>Isolated ADSCs: Purified and multiplied stem cells obtained by subjecting the SVF to a more advanced culture process in the laboratory.<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"Are_there_risks_or_limitations_of_Stem_Cell_treatment\"><\/span>Are there risks or limitations of Stem Cell treatment?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The clinical predictability of ADCT is more limited compared to AFT, and some important points should be taken into consideration.<\/p>\n<p>First of all, the fact that the procedure is &#8220;natural&#8221; does not mean that it is &#8220;risk-free.&#8221; Fat harvesting is a surgical procedure and carries some risks. These risks are:<\/p>\n<ul>\n<li>Bleeding<\/li>\n<li>Embolism<\/li>\n<li>Clot formation<\/li>\n<li>Hematomas<\/li>\n<li>Infection<\/li>\n<li>Edema (swelling)<\/li>\n<\/ul>\n<p>Secondly, the effectiveness of this treatment depends on how well the local microenvironment responds to these &#8220;signals,&#8221; depending on the patient\u2019s age and tissue health. This may cause high variability (heterogeneity) in the results from patient to patient.<\/p>\n<p>A third important point is the property of stem cells to promote &#8220;neoangiogenesis&#8221; (new blood vessel formation). Although this is generally a desired effect for revitalizing the skin, these treatments should be used with caution in patients with an oncological (cancer) history because of the theoretical potential to affect tumor growth or metastasis.<\/p>\n<p>Finally, unlike AFT (which has an FDA-approved protocol), stem cell treatments (SVF preparation methods, dosages, application protocols) do not yet have complete standardization. This can lead to inconsistent results between studies.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Which_autologous_treatment_is_better_Fibroblast_or_Stem_Cell\"><\/span>Which autologous treatment is better: Fibroblast or Stem Cell?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Choosing between these two autologous treatments is not about one being &#8220;better&#8221; than the other, but about what the therapeutic goal is. Both are valuable tools, but they are used for different purposes.<\/p>\n<ul>\n<li>Fibroblast Treatment (AFT) Should Be Preferred in the Following Situations:<\/li>\n<\/ul>\n<p>If the clinical goal is to structurally repair fixed, defined volume deficiencies and scars, AFT should be preferred. To fill &#8220;voids&#8221; such as deep nasolabial folds, depressed acne scars, or prominent scars, directly collagen-producing &#8220;factory&#8221; cells are needed. AFT provides a predictable and measurable volumetric response. Its logistics (punch biopsy) are simpler and safer.<\/p>\n<ul>\n<li>Stem Cell Treatment (ADCT) May Be Considered in the Following Situations:<\/li>\n<\/ul>\n<p>If the clinical goal is to improve the overall quality, texture, and elasticity of the skin and to give the skin a &#8220;bio-stimulation,&#8221; ADCT may be considered. In conditions such as thin, dull, lifeless skin and general loss of elasticity, these &#8220;signal-giving&#8221; cells may be more appropriate for enhancing the skin\u2019s general health and radiance. However, it should not be forgotten that ADCT is not a structural &#8220;filler,&#8221; but a &#8220;healer.&#8221;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Can_autologous_treatments_be_combined_with_procedures_such_as_Laser_or_Microneedling\"><\/span>Can autologous treatments be combined with procedures such as Laser or Microneedling?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Yes, and the most effective approaches in modern regenerative dermatology generally arise from this synergy. Combining controlled mechanical or thermal dermal damage (with laser or microneedling) with powerful biological stimulation (autologous cells) can provide much superior results than treatments performed alone.<\/p>\n<p>Fractional lasers or microneedling devices open thousands of microchannels in the skin and initiate a controlled wound healing process. This process increases both the penetration and effectiveness of topically applied autologous materials (stem cells, SVF, or PRP derivatives) under the skin.<\/p>\n<p>One of the greatest benefits of this combination is that it accelerates the recovery process. The biggest limitation of aggressive skin resurfacing techniques such as CO2 laser is the long recovery period that occurs after the procedure (redness, edema), in other words &#8220;downtime.&#8221; Applying autologous cellular components (especially ADCT\/SVF) immediately after the procedure actively regulates this inflammatory response, accelerates the repair of the upper layer of the skin, and minimizes discomfort.<\/p>\n<p>This combination approach allows more aggressive and effective energy devices to be used safely and increases patient satisfaction because the recovery period is dramatically reduced.<\/p>\n\t\t<\/div>\n\t\t\t\t\n<style>\n#col-1818226012 > .col-inner {\n  margin: 0px 0px -45px 0px;\n}\n<\/style>\n\t<\/div>\n\n\t\n<\/div>\n\t\t<\/div>\n\n\t\t\n<style>\n#section_1606412315 {\n  padding-top: 30px;\n  padding-bottom: 30px;\n}\n<\/style>\n\t<\/section>\n\t\n\n\t<section class=\"section\" id=\"section_1311919938\">\n\t\t<div class=\"section-bg fill\" >\n\t\t\t\t\t\t\t\t\t\n\t\t\t\n\n\t\t<\/div>\n\n\t\t\n\n\t\t<div class=\"section-content relative\">\n\t\t\t\n<div class=\"row\"  id=\"row-1175092289\">\n\n\t<div id=\"col-96960111\" class=\"col small-12 large-12\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n\t<div id=\"text-4252209934\" class=\"text\">\n\t\t\n<h2><span class=\"ez-toc-section\" id=\"Frequently_Asked_Questions\"><\/span>Frequently Asked Questions<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\t\t\n<style>\n#text-4252209934 {\n  font-size: 1.5rem;\n}\n<\/style>\n\t<\/div>\n\t\n<div class=\"accordion\">\n\t<div id=\"accordion-3409401320\" class=\"accordion-item\">\n\t\t<a id=\"accordion-3409401320-label\" class=\"accordion-title plain\" href=\"#accordion-item-how-does-autologous-fibroblast-and-stem-cell-treatment-slow-skin-aging?\" aria-expanded=\"false\" aria-controls=\"accordion-3409401320-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>How does autologous fibroblast and stem cell treatment slow skin aging?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-3409401320-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-3409401320-label\">\n\t\t\t\n<p>This treatment restores the skin\u2019s elasticity and firmness by increasing collagen production through fibroblasts and stem cells obtained from the patient\u2019s own cells. Thus, signs of aging decrease naturally.<\/p>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-944066080\" class=\"accordion-item\">\n\t\t<a id=\"accordion-944066080-label\" class=\"accordion-title plain\" href=\"#accordion-item-at-what-ages-can-autologous-fibroblast-and-stem-cell-treatment-be-applied?\" aria-expanded=\"false\" aria-controls=\"accordion-944066080-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>At what ages can autologous fibroblast and stem cell treatment be applied?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-944066080-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-944066080-label\">\n\t\t\t\n<p>It is generally recommended for individuals over the age of 25 whose skin elasticity has started to decrease. However, it can also be used protectively in the early period for skin renewal; the individual situation should be evaluated by a dermatologist.<\/p>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-1562124368\" class=\"accordion-item\">\n\t\t<a id=\"accordion-1562124368-label\" class=\"accordion-title plain\" href=\"#accordion-item-what-is-the-difference-between-stem-cell-treatment-and-fibroblast-application?\" aria-expanded=\"false\" aria-controls=\"accordion-1562124368-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>What is the difference between stem cell treatment and fibroblast application?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-1562124368-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-1562124368-label\">\n\t\t\t\n<p>While stem cells have the ability to transform into different cells, fibroblasts are especially responsible for collagen production. Combined application supports both the renewal and repair process.<\/p>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-3459615767\" class=\"accordion-item\">\n\t\t<a id=\"accordion-3459615767-label\" class=\"accordion-title plain\" href=\"#accordion-item-how-long-does-the-permanence-of-autologous-fibroblast-and-stem-cell-treatment-last?\" aria-expanded=\"false\" aria-controls=\"accordion-3459615767-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>How long does the permanence of autologous fibroblast and stem cell treatment last?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-3459615767-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-3459615767-label\">\n\t\t\t\n<p>Results generally last between 1.5 and 3 years. However, factors such as skin type, age, and lifestyle may affect the duration of permanence. The duration of the effect can be extended with regular maintenance sessions.<\/p>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-2947509116\" class=\"accordion-item\">\n\t\t<a id=\"accordion-2947509116-label\" class=\"accordion-title plain\" href=\"#accordion-item-who-is-this-treatment-not-suitable-for?\" aria-expanded=\"false\" aria-controls=\"accordion-2947509116-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>Who is this treatment not suitable for?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-2947509116-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-2947509116-label\">\n\t\t\t\n<p>It is not recommended for people with active infection, autoimmune disease, a history of cancer, or those who are pregnant. Suitability is determined after a detailed dermatological examination.<\/p>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-2366623728\" class=\"accordion-item\">\n\t\t<a id=\"accordion-2366623728-label\" class=\"accordion-title plain\" href=\"#accordion-item-does-autologous-fibroblast-treatment-have-side-effects?\" aria-expanded=\"false\" aria-controls=\"accordion-2366623728-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>Does autologous fibroblast treatment have side effects?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-2366623728-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-2366623728-label\">\n\t\t\t\n<p>Since the treatment is performed with person-specific cells, the risk of allergy or rejection is very low. Mild redness, edema, or bruising may occur in the application area for a short time.<\/p>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-2834180503\" class=\"accordion-item\">\n\t\t<a id=\"accordion-2834180503-label\" class=\"accordion-title plain\" href=\"#accordion-item-what-is-the-recovery-process-like-after-stem-cell-and-fibroblast-treatment?\" aria-expanded=\"false\" aria-controls=\"accordion-2834180503-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>What is the recovery process like after stem cell and fibroblast treatment?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-2834180503-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-2834180503-label\">\n\t\t\t\n<p>Redness and sensitivity generally decrease within a few days. Over time, the skin gains a brighter, more vibrant, and smoother appearance. The full effect becomes apparent within 3-6 months.<\/p>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-3104326191\" class=\"accordion-item\">\n\t\t<a id=\"accordion-3104326191-label\" class=\"accordion-title plain\" href=\"#accordion-item-is-autologous-fibroblast-and-stem-cell-treatment-effective-for-acne-scars?\" aria-expanded=\"false\" aria-controls=\"accordion-3104326191-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>Is autologous fibroblast and stem cell treatment effective for acne scars?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-3104326191-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-3104326191-label\">\n\t\t\t\n<p>Yes, it provides significant improvement especially in atrophic acne scars by repairing the skin tissue. Thanks to new collagen production, the skin surface becomes smoother.<\/p>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-3393138476\" class=\"accordion-item\">\n\t\t<a id=\"accordion-3393138476-label\" class=\"accordion-title plain\" href=\"#accordion-item-can-this-treatment-be-applied-together-with-other-aesthetic-procedures?\" aria-expanded=\"false\" aria-controls=\"accordion-3393138476-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>Can this treatment be applied together with other aesthetic procedures?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-3393138476-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-3393138476-label\">\n\t\t\t\n<p>Yes, it can be combined with PRP, mesotherapy, or laser treatments. However, the order and intervals of application should be determined according to the doctor\u2019s planning.<\/p>\n\t\t<\/div>\n\t<\/div>\n\t\n\t<div id=\"accordion-658043881\" class=\"accordion-item\">\n\t\t<a id=\"accordion-658043881-label\" class=\"accordion-title plain\" href=\"#accordion-item-what-factors-affect-the-price-of-autologous-fibroblast-and-stem-cell-treatment?\" aria-expanded=\"false\" aria-controls=\"accordion-658043881-content\">\n\t\t\t<button class=\"toggle\" aria-label=\"Toggle\"><i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/button>\n\t\t\t<span>What factors affect the price of autologous fibroblast and stem cell treatment?<\/span>\n\t\t<\/a>\n\t\t<div id=\"accordion-658043881-content\" class=\"accordion-inner\" aria-labelledby=\"accordion-658043881-label\">\n\t\t\t\n<p>The price varies according to the amount of cells obtained, laboratory procedures, number of sessions, and the application area. Since personalized planning is made, the exact fee is determined after examination.<\/p>\n\t\t<\/div>\n\t<\/div>\n\t\n<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n<\/div>\n\t\t<\/div>\n\n\t\t\n<style>\n#section_1311919938 {\n  padding-top: 30px;\n  padding-bottom: 30px;\n}\n<\/style>\n\t<\/section>\n\t\n\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":2271,"parent":2087,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-blank.php","meta":{"footnotes":""},"class_list":["post-2272","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/drsevalkarasati.com\/en\/wp-json\/wp\/v2\/pages\/2272","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drsevalkarasati.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/drsevalkarasati.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/drsevalkarasati.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/drsevalkarasati.com\/en\/wp-json\/wp\/v2\/comments?post=2272"}],"version-history":[{"count":3,"href":"https:\/\/drsevalkarasati.com\/en\/wp-json\/wp\/v2\/pages\/2272\/revisions"}],"predecessor-version":[{"id":2318,"href":"https:\/\/drsevalkarasati.com\/en\/wp-json\/wp\/v2\/pages\/2272\/revisions\/2318"}],"up":[{"embeddable":true,"href":"https:\/\/drsevalkarasati.com\/en\/wp-json\/wp\/v2\/pages\/2087"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/drsevalkarasati.com\/en\/wp-json\/wp\/v2\/media\/2271"}],"wp:attachment":[{"href":"https:\/\/drsevalkarasati.com\/en\/wp-json\/wp\/v2\/media?parent=2272"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}